DBRM course program 2010

Courses offered at Bachelor level

• DBRM contributes to undergraduate education by supplying expertise in Stem Cell Biology and Regenerative Medicine, and by promoting excellence in education in the Medicine programme and the Biomedicine programme at Bachelor level at Karolinska Institutet.

Courses offered at Master level

• Advanced course in Stem Cell Biology and Regenerative Medicine 30 hp (August 30, 2010 - January 16, 2011)

This advanced undergraduate course is both theoretical and experimental. The course is open to students interested in the area of stem cell biology and regenerative medicine. After the course, the students should know the basics of stem cell biology and the medical use of cell therapy. The students should be able to apply and understand the theoretical basis for key technologies utilized in stem cell research. The course covers key concepts in translational research from the laboratory to the clinic. The course consists of lectures, seminars, group discussions, training in writing grant applications and a practical experimental project carried out at a stem cell research laboratory. The course spans the entire Autumn semester.

• Advanced course in Stem Cell Biology and Regenerative Medicine 10 hp (August 30 - October 1, 2010)

This course is one of the different profiles offered for the third semester of the Master's degree programme in Biomedicine at Karolinska Institutet. After the course, the students should know the basics of stem cell biology and the medical use of cell therapy. The students should be able to apply and understand the theoretical basis for key technologies utilized in stem cell research. The course covers key concepts in translational research from the laboratory to the clinic. The course consists of lectures, seminars, group discussions and training in writing grant applications. Note that only students already accepted into the Masters program in Biomedicine qualify for this course.

Courses offered at Doctoral level

• Academic careers and Research financing (January 27 - February 27 2010)

This course covers the structure and function of academic institutions, financing of research activities including resource allocation, projects, conferences, research networks and collaboration projects, and different academic career paths. A major emphasis will be placed on the different strategic decisions made in conjunction with the transitions from postgraduate to postdoctoral to assistant professorship. The target group is doctoral students and post-doc researchers. Link to the course home pages at DBRM Research School and at KI career service.

• Molecular Localisation in Cells Using Fluorescence Microscopy (February 15 - February 26)

The course contains both theoretical and practical modules or demonstrations focusing on the different techniques used for investigating molecular localisation in cells. These include different types of microscopes, sample preparation, immunostaining and visualization, and data analysis. The course is doctoral level course at 3.0 ECTS credit points. The course director is Dr. Piergiorgio Percipalle and the course co-director is Dr. Emilie Louvet. Link to course home pages.

• Bioinformatics for Cell Biologists (March 15 - 19 2010)

This postgraduate level course provides essential, practical knowledge about computational and bioinformatics methods for cell biologists, specifically in developmental biology. The course director is Rickard Sandberg. Link to course home pages.

• Genetics and epigenetics in stem cell biology (March 22-26, 2010)

This doctoral level course presents state-of-the-art advances in the understanding of genetics and epigenetic processes underlying the regulatory principles in stem cell biology. The course co-directors are Dr. Ola Hermanson and Dr. Jonas Muhr.

• Medical and developmental genetics (May 17 - 21, 2010)

This one-week course provides a view on how genes and genomes together with environmental factors affect human beings in disease, and in normal development and tissue maintenance. After the course, the students should be able to describe the principles and methods of modern medical genetics aimed in improving human health. The course is co-organized by DBRM and the Doctoral course program in Regenerative medicine at Karolinska Institutet. Link to course pages.

• High resolution and correlative techniques (June 8 - 10, 2010)

This year the course in high-resolution and correlative techniques is combined with the SCANDEM2010 international meeting ( www.scandem.org), which will be held in Stockholm, Kista Electrum, on 8-10th of June. All students, post-docs (and even researchers and group leaders) are welcome to register for the meeting. The deadline is May 1. The very first day of the meeting will include workshops for students and technicians. Download SCANDEM_program.

DBRM students and post-docs who want to participate in the workshops listed in the program should not register through the main registration system of the meeting. The course director is Oleg Shupliakov, email Oleg.Shupliakov@ki.se

• Developmental Biology for Regenerative Medicine (August 30 - September 10, 2010)

This two-week course provides an advanced review of developmental biology - both descriptive and molecular, and an introduction to regenerative medicine including key concepts in translational research from the laboratory to the clinic. Link to home pages.

• Stem Cell Biology and Bioinformatics Tools (September 16 - 22, 2010)

This one-week postgraduate course presents researchers with important bioinformatic analysis skills used in the study of stem cells. The course consists of lectures, computer exercises and case studies. Students have the opportunity to provide example problems. The course is organized in collaboration with Griffith University in Australia. Link to course pages.

• Stem Cells and Neurodegenerative Disorders (September 27 - October 1, 2010)

This course presents an overview of common neurodegenerative disorders from the perspective on regenerative medicine and development of novel therapies. After the completed course, the students are able to discuss the known mechanisms and causes underlying the development of the most common neurodegenerative disorders and to describe development of novel therapies for these disorders. The course is Dr. Eva Hedlund, The Stockholm Branch of the Ludwig Institute for Cancer Research, email eva.hedlund@licr.ki.se and the course co-director is Dr. Rosario Sanchez Pernaute, email rpernaute@inbiomed.org. Link to course pages.

• Molecular Localisation in Cells Using Fluorescence Microscopy (September 29 - October 8)

The course contains both theoretical and practical modules or demonstrations focusing on the different techniques used for investigating molecular localisation in cells. These include different types of microscopes, sample preparation, immunostaining and visualization, and data analysis. The course is doctoral level course at 3.0 ECTS credit points. The course director is Dr. Piergiorgio Percipalle and the course co-director is Dr. Emilie Louvet. Link to course home pages.

• Signaling cascades cross talking to Notch in development and pathology (October 11 - 12)

This theoretical two-day course focuses on how Notch signaling intersects with other signaling mechanisms, and how this cross-talk is manifested both during normal development and in pathology. More specifically, the course addresses how Notch signaling is involved in cell fate determination during normal embryonic developmentand in the adult organism, and how deranged Notch signaling contributes to various pathologies. Topics include Notch/BMP-TGF-�beta, Notch/hypoxia, Notch/PI3kinase cross�talk and the role of Notch in neurogenesis, vasculogenesis,heamatopoietic development, cardiology and epithelial-�mesenchymal transition. Contact András Simon (andras.simon@ki.se) for information. Course information with schedule.

• Functional architecture of the cell nucleus (November 24 - 30)

A joint international doctoral course on the subject “Functional Architecture of the Cell Nucleus” between the RIKEN Yokohama institute Omics Science Center and Karolinska Institutet Department of Cell and Molecular Biology (Sweden) will take place from November 24th to 30th at the RIKEN Yokohama Institute (Supported by The Molecular Biology of Japan).

The course directors are Dr. Matti Nikkola (matti.nikkola@ki.se) and Dr. Carsten Daub (daub@gsc.riken.jp).

The complete course pages in Japan can be found at at http://www.osc.riken.jp/english/event/cell2010 and in Sweden at the local course pages.