Protein Structure

Protein name: Tyrosine-protein kinase BTK

Organism: Homo sapiens (Human)

Sequence length: 659 AA.

Subcellular location: Cytoplasm, Membrane, Nucleus

Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

Belongs to the protein kinase superfamily

Domains: Contains 1 Btk-type zinc finger.

Contains 1 PH domain.

Contains 1 protein kinase domain.

Contains 1 SH2 domain.

Contains 1 SH3 domain.

The 3D structure of BTK is still unknown.

Some of the domain of BTK:

Crystal structure of PH domain and BTK motif of Bruton's tyrosine kinase

Single crystal X-ray diffraction, resolution 1.60Å

protein kinase domain.

SH2 domain

Sh3 domain

Sequence similarity:

Alignments