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PREVIOUS PUBLICATIONS

SELECTED "CLASSICS" FROM DBRM RESEARCHERS

Before the start of DBRM, DBRM PI:s had since 1990 contributed to over 150 publications regarded as "Highly Cited" by ISI. This is a selection of 25 of those published between 1990-2000 in chronological order:


Lendahl U, et al. (1990) CNS stem cells express a new class of intermediate filament protein.. Cell 60:585-595. [UL]

Ernfors P, et al. (1990) Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proc Natl Acad Sci USA 87:5454-5458. [PE, CFI]

Ernfors P, et al. (1990) Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron 5:511-526. [PE]

Ibanez CF, et al. (1992) Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentitation by binding to the Trk gene product. Cell 69: 329-341. [CFI]

Lardelli M, et al. (1994) The novel Notch homolog mouse Notch-3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech Dev 46:123-136. [UL]

Ernfors P, et al. (1994) Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77:503-512. [PE]

Ernfors P, et al. (1994) Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368:147-150. [PE]

Simon A, et al. (1995) The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases. J Biol Chem 270: 1107-1112. [AS]

Perlmann T and Jansson L (1995) A novel pathway for vitamin-A signaling mediated by RXR heterodimerization with NGFI-B and Nurr1. Genes Dev 9:769-782. [TP]

Pieribone VA, et al. (1995) Distinct pools of synaptic vesicles in neurotransmitter release. Nature 375:493-497. [OS, LB]

Trupp M, et al. (1995) Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol 130:137-148. [CFI, EA]

Ericson J, et al. (1995) Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for venrtral patterning within the ventral tube. Cell 81:747-756. [JE, JM]

Sanchez MP, et al. (1996) Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70-73. [JF]

Trupp M, et al. (1996) Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381:785-789. [CFI, EA]

Ericson J, et al. (1996) Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell 87:661-673. [JE]

Ericson J, et al. (1997) Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90:169-180. [JE]

Shupliakov O, et al. (1997) Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions. Science 276:259-263. [LB, OS]

Zetterström RH, et al. (1997) Dopamine neuron agenesis in Nurr1-deficient mice. Science 276:248-250. [TP]

Frisén J, et al. (1998) Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system. Neuron 20:235-243. [JF]

Kliewer SA, et al. (1998) An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell 92:73-82 [TP]

Wagner J, et al. (1999) Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat Biotechnol 17:653-659. [EA, TP]

Johansson CB, et al. (1999) Identification of a neural stem cell in the adult mammalian central nervous system. Cell 96:25-34. [JF, UL]

Clarke DL, et al. (2000) Generalized potential of adult neural stem cells. Science 288:1660-1663. [JF, UL]

Jepsen K, et al. (2000) Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102: 753-763. [OH]